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Free HESI A2 Anatomy & Physiology Practice Questions (2026)

Original HESI A2 anatomy & physiology practice with written answers. Try the free samples below, then get all 10 anatomy & physiology questions in the full $39 bank.

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What the HESI A2 Anatomy & Physiology section tests

Anatomy & Physiology asks how the body is organised: directional terms, the levels from cell to tissue to organ to system, and the major organ systems with their main functions. A systems-level map — what each system does and how the pieces fit together — is usually more useful here than memorising isolated facts.

Read first. These are original practice questions written for study. They are not real HESI A2 exam items and are not affiliated with or endorsed by Elsevier or HESI. No nurse or clinician reviewed this content. We make no pass-rate or score guarantee.

Free Anatomy & Physiology practice questions

1. A nurse describes a wound on the patient's forearm as being located proximal to the wrist. Which statement best explains this term?

A. The wound is closer to the fingertips than the wristB. The wound is closer to the elbow than the wristC. The wound is on the back surface of the forearmD. The wound is on the side of the forearm away from the midline
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Answer: B. Proximal means nearer to the point of attachment to the trunk, so a site proximal to the wrist lies closer to the elbow.

2. Which chamber of the heart pumps oxygenated blood into the systemic circulation?

A. Right atriumB. Right ventricleC. Left atriumD. Left ventricle
Show answer & explanation

Answer: D. The left ventricle has the thickest wall and ejects oxygen-rich blood through the aorta to the body.

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Part of the full 68-question HESIReady exam. One payment of $39, every section, with explanations.

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Questions people ask

Is this HESI A2 anatomy & physiology practice free?

Yes. These sample Anatomy & Physiology questions are free with full explanations. The complete bank has 10 anatomy & physiology questions, part of the 68-question HESIReady exam for a one-time $39.

What does the HESI A2 Anatomy & Physiology section cover?

Anatomy & Physiology asks how the body is organised: directional terms, the levels from cell to tissue to organ to system, and the major organ systems with their main functions. A systems-level map — what each system does and how the pieces fit together — is usually more useful here than memorising isolated facts.